Core Programs

Publications

Myopia

Quinn GE, Berlin JA, Young TL, Ziylan S, Stone RA. An association of intraocular pressure and myopia in children. Ophthalmology 1995; 102: 180-6.

Young TL, Weis JR, Summers CG, Egbert JE. The association of strabismus, amblyopia, and refractive errors in spasmus nutans. Ophthalmology 1997; 104:112-17.

Cheung JC, Summers CG, Young TL. Myopia predicts better outcome in persistent hyperplastic primary vitreous. J Pediatr Ophthalmol Strabismus 1997; 34:170-6.

Young TL, Ronan S, Alvear A, Drahozal L, Wildenberg SC, Oetting WS, Atwood L, Wilkin, D, King R. Evidence that a locus for familial high myopia maps to chromosome 18p. Am J Hum Genet 1998; 63:109-119.

Young TL, Ronan S, Alvear A, Wildenberg SC, Oetting WS, Atwood L, Wilkin D, King RA. A second locus for familial high myopia on chromosome 12q. Am J Hum Genet 1998; 63:1419-1424.

Oetting WS, Armstrong-Jacobs CM, Ronan SM, Young TL, Sellers TA, King RA. Multiplexed short tandem repeat polymorphisms of the Weber 8A set of markers using infrared fluorescence and M13 tailed primers. Electrophoresis 1998, 19,3079-3083.

Young TL, Atwood LD, Ronan SM, Dewan AT, Alvear AB, Peterson J, Holleschau A, King RA. Further refinement of the MYP2 locus for autosomal dominant high myopia by linkage disequilibrium analysis. Ophthalmic Genetics 2001;22:69-75.

Paluru P, Heon E, Devoto M, Ronan SM, Wildenberg SC, Scavello G, Holleschau A, Makitie O, Cole WG, King RA, Young TL. A new locus for autosomal dominant high myopia maps to the long arm of chromosome 17. Invest Ophthalmol Vis Sci 2003; 44:1830-1836.

Young TL, Guo XD, Scavello G, Johnson J, King RA, Rada JA. Identification of genes expressed in a human scleral cDNA library. Mol Vis 2003; 9:508-514.

Young TL, Deeb SS, Ronan SM, Dewan AT, Alvear AB, Scavello GS, Paluru PC, Brott MS, Haya shi T, Holleschau AM, Benegas N, Schwartz M, Atwood LD, Oetting WS, Rosenberg T, Motulsk y AG, King RA. X-linked high myopia associated with cone dysfunction. Arch Ophthalmol, Jun 2004;122:897-908.

Paluru PC, Scavello GS, Ganter W, Young TL. Exclusion of Lumican and Fibromodulin as candidate genes in MYP3-linked high-grade myopia. Mol Vis 2004;10:917-922.

Scavello GS, Paluru PC, Ganter WR, Young TL. Sequence variants in the Transforming Growth Beta-Induced Factor (TGIF) gene are not associated with high myopia. Invest Ophthalmol Vis Sci 2004;45(7):2091-2097.

Young TL, Scavello G, Paluru P, Choi J, Rappaport EF, Rada JA. Microarray analysis of gene expression in human donor sclera. Mol Vis . 2004;10:163-76.

Young TL. Dissecting the genetics of human high myopia: A molecular biologic approach. Trans Am Ophthalmol Soc 2004;52:432-446.

Scavello GS, Paluru PC, Zhou J, White PS, Rappaport EF, Young TL. Genomic structure and organization of the high grade myopia-2 locus (MYP2) critical region: mutation screening of 9 positional candidate genes. Mol Vis 2005; 11:97-110.

Zhou J, Young TL. Evaluation of LIPIN2 as a candidate gene for autosomal dominant 1 high-grade. myopia. Gene. 2005;352:10-19.

Paluru PC, Nallasamy S, Devoto M, Rappaport EF, Young TL. Identification of a novel locus on chromosome 2q for autosomal dominant high-grade myopia. Invest Ophthalmol Vis Sci 2005;46(7):2300-2307.

Heidary G, Ying G-S, Maguire MG, Young TL. The association of sphere on cylinder type and severity in a high myopia cohort. Optom Vis Sci Apr 2005;82(4):244-7.

Zhou J, Rappaport EF, Tobias JW, Young TL. Differential gene expression in mouse sclera during ocular development. Invest Ophthalmol Vis Sci 2006;47:1794-1802.

Johnson JM, Young TL, Summers-Rada JA. Small leucine rich repeat proteoglycans (SLRPs) in the human sclera: identification of abundant levels of PRELP. Mol Vis 2006;12:1057-66.

Young TL, Metlapally R, Shay A. Complex trait genetics of refractive error. Arch Ophthalmol, Jan 2007;125:38-48.

Nallasamy S, Paluru PC, Devoto M, Wasserman NF, Zhou J, Young TL. Genetic linkage study of high-grade myopia in a Hutterite population from South Dakota. Mol Vis 2007,13:229-36.

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