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Methodological Development

Boyles AL, Scott WK, Martin ER, Schmidt S, Li YJ, Ashley-Koch A, Bass MP, Pericak-Vance MA, Speer MC, Hauser ER. Linkage disequilibrium inflates Type I error rates in multipoint linkage analysis when parental genotypes are missing. Hum Hered 2005;59:220-227. Epub 2005 July 27.

Stenger JE, Xu H, Haynes C, Hauser ER, Pericak-Vance MA, Goldschmidt-Clermont PJ, Vance JM. Statistical Viewer: a tool to upload and integrate linkage and association data as plots displayed within the Ensembl genome browser. BMC Bioinformatics 6:95, 2005.

Schmidt MA, Hauser ER, Martin ER, Schmidt S. Extension of the SIMLA package for generating pedigrees with complex inheritance patterns: Environmental covariates, gene-gene and gene-environment interaction (2005) Stat Appl Genet Mol Biol 4(1): article 15.

Sawcer SJ, Maranian M, Singlehurst S, Yeo T, Compston A, Daly MJ, De Jager PL, Gabriel S, Hafler DA, Lander ES, Rioux JD, Walsh E, Gregory SG, Schmidt S, Pericak-Vance MA, Barcellos L, Hauser SL, Oksenberg JR, Kenealy SJ, Haines JL. Enhancing linkage analysis of complex disorders: An evaluation of high-density genotyping. Hum Mol Genet. 2004 Sep 1;13(17):1943-9. Epub 2004 Jul 6.

Hauser ER, Watanabe R, Duren W, Bass M, Langefeld C, Boehnke M. Ordered subset analysis in genetic linkage mapping of complex traits. Genetic Epidemiology, 27:1, 53-63 Published Online: 8 Apr 2004 .

Hauser ER, Mooser V, Crossman DC, Haines JL, Jones CH, Winkelmann BR, Schmidt S, Scott WK, Roses AD, Pericak-Vance MA, Granger CB, Kraus WE; Design of the Genetics of Early Onset Cardiovascular Disease study (GENECARD). Am Heart J 145(4):602-13, 2003.

Martin ER, Bass MP, Gilbert JR, Pericak-Vance MA, Hauser ER. Genotype-based association test for general pedigrees: The genotype-PDT. Genet Epidemiol. 25(3):203-13,2003.

Martin ER, Bass MP, Hauser ER, Kaplan NL. (2003) Accounting for linkage in family-based tests of association with missing parental genotypes. Am J Hum Genet. 73:1016-1026, 2003.

Matise TC, Sachidanandam R, Clark AG, Kruglyak L, Wijsman E, Kakol J, Buyske S, Chui B, Cohen P, de Toma C, Ehm M, Glanowski S, He C, Heil J, Markianos K, McMullen I, Pericak-Vance MA, Silbergleit A, Stein L, Wagner M, Wilson AF, Winick JD, Winn-Deen ES, Yamashiro CT, Cann HM, Lai E, Holden AL. A 3.9-centimorgan-resolution human single-nucleotide polymorphism linkage map and screening set. Am J Hum Genet. 73(2):271-84, 2003.

Hauser ER, Hsu FC, Daley D, Olson JM, Rampersaud E, Lin JP, Paterson AD, Poisson LM, Chase GA, Dahmen G, Ziegler A. (2003) Effects of covariates: Summary of group 5 contributions. Genetic Epidemiology, 25:S1, S43-S49 Published Online: 14 Nov 2003.

Rampersaud E, Allen A, Li YJ, Shao Y, Bass M, Haynes C, Ashley-Koch A, Martin ER, Schmidt S, Hauser ER. (2003) Adjusting for covariates on a slippery slope: Linkage analysis of change over time. BMC Genetics 2003, 4(Suppl 1):S50 .

Schmidt S, Shao Y, Hauser ER, Slifer SH, Martin ER, Scott WK, Speer MC, Pericak-Vance MA. Life after the screen: making sense of many p-values. Genetic Epidemiology 21(Suppl 1): S546-S551, 2001.

Oliveira SA, Scott WK, Pericak-Vance MA, Vance, JM. Dissecting a complex disease using modern techniques of molecular biology. Lab Med 10(32):594-598, 2001.

Martin ER, Monks SA, Warren LL, Kaplan N. A test for linkage and association in general pedigrees: The pedigree disequilibrium test (PDT). Am J Hum Genet 67:146-154, 2000.

Martin ER, Lai EH, Gilbert JR, Rogala AR, Afshari AJ, Riley J, Finch KL, Stevens JF, Livak KJ, Slotterbeck BD, Slifer SH, Warren LL, Conneally PM, Schmechel DE, Purvis I, Pericak-Vance MA, Roses AD, Vance J. SNPing away at complex diseases: Analysis of SNPs around APOE in Alzheimer disease. Am J Hum Genet 67:383-394, 2000.

Hauser ER and Pericak-Vance MA. Genetic analysis for common complex disease. Am Heart J, 140:S36-S44, 2000.

Manasco P, Rieser P, and Pericak-Vance M.  Genes; Here Today Gone Tomorrow:  A Clinician's Guide to Genetic Linkage & Association Studies. The Endocrinologist:10(5):328-334, 2000.

Allison DB, Heo M, Kaplan NL, Martin ER. Sibling-based tests of linkage and association for quantitative traits. Am J Hum Genet 64:1754- 1763, 1999.

Kaplan NL, Martin ER, Morris RW, Weir BS. Marker selection for the transmission/disequilibrium test in recently admixed populations. Am J Hum Genet 62:703-712, 1998.

Hauser ER, Boehnke M. Genetic linkage analysis of complex genetic traits by using affected sibling pairs. Biometrics 54:1238-1246, 1998.

Kaplan NL, Martin ER, Weir BS. Power studies for the transmission/disequilibrium tests with multiple alleles. Am J Hum Genet 60:691-702, 1997.

Martin ER, Kaplan NL, Weir BS. Tests for linkage and association in nuclear families. Am J Hum Genet 61:493-503, 1997.

Martin ER, Weir BS, Kaplan NL. A transmission/disequilibrium test for identifying quantitative trait loci. Am J Hum Genet 61(Suppl): A284, 1997.

Scott WK, Pericak-Vance MA, Haines JL. Genetic analysis of complex diseases. Science 275:1327, 1997.

Ghosh S, Karanjawala ZE, Hauser ER, Ally D, Knapp JI, Rayman JB, Musick A, Tannenbaum J, Te C, Shapiro S, Eldridge W, Musick T, Martin C, Smith JR, Carpten JD, Brownstein MJ, Powell JI, Whiten R, Chines P, Nylund SJ, Magnuson VL, Boehnke M, Collins FS. Methods for precise sizing, automated binning of alleles, reduction of error rates in large-scale genotyping using fluorescently labeled dinucleotide markers. Genome Research 7:165-178, 1997.

Hauser ER, Boehnke M, Guo SW, Risch N. Affected-sib-pair interval mapping and exclusion for complex genetic traits: Sampling considerations. Genetic Epidemiology 13:17-137, 1996.

 

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