Successes

Core Faculty

Elizabeth R. Hauser, PhD, is an Associate Professor in the Section of Medical Genetics, Department of Medicine. Dr. Hauser is a statistical geneticist with experience in the development and application of methods for the analysis of affected sibling pair data in studies of complex genetic disorders. Her current research interests include cardiovascular genetics, informatics, and methodologic developments for complex diseases.

MHS, 1985, Epidemiology/Genetic Epidemiology, The Johns Hopkins University, School of Hygiene and Public Health
MS, 1992, Biostatistics, University of Michigan, Ann Arbor, MI
PhD, 1998, Biostatistics, University of Michigan, Ann Arbor, MI

Selected Publications

Hauser ER, Crossman DC, Granger CB, Haines JL, Jones CJH, Mooser V, McAdam B, Winkelmann BR, Wiseman AH, Muhlestein JB, Bartel AG, Dennis CA, Dowdy E, Estabrooks S, Eggleston K, Francis S, Roche K, Clevenger PW, Huang L, Pedersen B, Shah S, Schmidt S, Haynes C, West S, Asper D, Booze M, Sharma S, Sundseth S, Middleton L, Roses A, Hauser MA, Vance JM, Pericak-Vance MA, Kraus WE. A Genome Wide Scan for Early-Onset Coronary Artery Disease in 438 Families: The GENECARD Study. Am J Hum Genet 75(3):436-437, 2004.

Hauser ER, Watanabe R, Duren W, Bass M, Langefeld C, Boehnke M. Ordered subset analysis in genetic linkage mapping of complex traits. Genetic Epidemiology 27(1):53-63, 2004.

Bass MP, Martin ER, Hauser ER: Pedigree Generation for Analysis of Genetic Linkage and Association. In: Altman RB, Dunker AK, Hunter L, Jung TA, Klein TE. eds., Pacific Symposium on Biocomputing, World Scientific, New Jersey, 2004.

Martin ER, Bass MP, Hauser ER, Kaplan NL. (2003) Accounting for linkage in family-based tests of association with missing parental genotypes. Am J Hum Genet, 73(6):1016-26.

Hauser ER, Mooser V, Crossman D, Haines J, Jones C, Winkelmann B, Schmidt S, Scott WK, Roses A, Pericak-Vance M, Granger C, Kraus W. Design of the genetics of early onset cardiovascular disease (GENECARD) study. American Heart Journal 145:602-613, 2003.

Ghosh S, Watanabe RM, Hauser ER, Valle T, Magnuson VL, Erdos MR, Langefeld CD, Balow J, Ally DS, Kohtamaki K, Chines P, Birznieks G, Kaleta HS, Musick A, Te C, Tannenbaum J, Eldridge W, Shapiro S, Martin C, Witt A, So A, Chang J, Shurtleff B, Porter R, Kudelko K, Unni A, Segal L, Sharaf R, Blaschak-Harvan JB, Eriksson J, Tenkula T, Vidgren G, Ehnholm C, Tuomilehto-Wolf E, Hagopian W, Buchanan TA, Tuomilehto J, Bergman RN, Collins FS, Boehnke M. Type 2 diabetes: Evidence for linkage on chromosome 20 in 716 Finnish affected sib pairs. PNAS 96(5):2198-2203, 1999.

Hauser ER, Boehnke M. Genetic linkage analysis of complex genetic traits by using affected sibling pairs. Biometrics 54:1238-1246, 1998.

Ghosh S, Karanjawala ZE, Hauser ER, Ally D, Knapp JI, Rayman JB, Musick A, Tannenbaum J, Te C, Shapiro S, Eldridge W, Musick T, Martin C, Smith JR, Carpten JD, Brownstein MJ, Powell JI, Whiten R, Chines P, Nylund SJ, Magnuson VL, Boehnke M, Collins FS. Methods for precise sizing, automated binning of alleles, reduction of error rates in large-scale genotyping using fluorescently labeled dinucleotide markers. Genome Research 7:165-178, 1997.

Hauser ER, Boehnke M, Guo SW, Risch N. Affected-sib-pair interval mapping and exclusion for complex genetic traits: Sampling considerations. Genetic Epidemiology 13:17-137, 1996.

Chamberlain JS, Boehnke M, Frank TS, Kiousis S, Xu J, Guo SW, Hauser ER, Norum RA, Helmbold EA, Markel D, Keshavarzi SM, Jackson CE, Calzone K, Garber J, Collins FS, Weber BL. BRCA1 maps proximal to D17S579 on chromosome 17q21 by genetic analysis. Am J Human Genet 52:792-798, 1993.

Contact at:
Center for Human Genetics
DUMC Box 3445
Durham, NC 27710
Phone: 1-919-684-0603
Fax: 1-919-684-0913
E-mail: Elizabeth.Hauser@duke.edu

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